Neuroscience · Neurotechnology · CMOS Interfaces

BRAIN-DRIVEN TECHNOLOGY

“As followers of natural science we know nothing of any relation between thoughts and the brain, except as a gross correlation in time and space.”
— Charles Scott Sherrington

Profile photo of Om Kolhe

I am a PhD candidate at Purdue University, working under the mentorship of Prof. Krishna Jayant in the Nano Neurotechnology Lab. My research focuses on understanding the neural mechanisms of learning and decision-making by developing novel technologies and experimental protocols. I am particularly interested in how neurons communicate and coordinate across multiple modalities to perform computations that are both robust and plastic.

I earned a dual degree (B.Tech + M.Tech) in Electrical Engineering from the Indian Institute of Technology (IIT) Bombay in August 2020. For my Master’s thesis, I worked with Prof. Maryam Shojaei Baghini to design a multi-phase oscillator for next-generation 5G receivers. During my undergraduate studies, I worked under Prof. Shalabh Gupta on the front-end design of an IRNSS receiver.

AREA 01

Neural Dynamics of Learning and Movement

Mechanisms underlying reliable motor output

Mechanisms underlying reliable motor output

I am investigating the neural basis of skilled movement, focusing on how distinct brain regions coordinate activity to support precise and reliable behavior.

In collaboration with Hammad Khan. Manuscript currently in revision.

AREA 02

Neurotechnology Platforms

Multimodal Neural Recording Platform

Multimodal Neural Recording Platform

We developed a chronic platform for simultaneous electrophysiological recording and two-photon calcium imaging using transparent, flexible surface μECoG arrays.

In collaboration with Alec Booth. Paper

3D electrodes for mapping cortical dynamics

3D electrodes for mapping cortical dynamics

We are developing three-dimensional electrode arrays to capture electrical activity across a volume of brain tissue rather than only along a surface or a line.

AREA 03

Neural Interface Electronics

ASIC for simultaneous electrophysiology and electrochemistry

ASIC for simultaneous electrophysiology and electrochemistry

This ASIC enables simultaneous electrophysiological and electrochemical recordings, allowing subtle changes in dopamine levels to be measured alongside neural dynamics.

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Publications

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Patents

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Presentations

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For collaborations, research questions, or opportunities, reach me through email or academic/social platforms.